How Long Does PRAZIPRO Take to Work?

How Long Does PRAZIPRO Take to Work?

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Keeping a fish tank clean and pristine is the number one challenge for many aquarists. Fish waste, algae, food and other organisms can create an environment that’s unhealthy and toxic. Luckily, there are many things we can use to keep the tank clean while ensure our fish’s health.

PRAZIPRO is a good product, but how long does it take to work? There are many aspects and factors to consider when using PRAZIPRO, but on average it will take anywhere from four to five days with twice per day dosing to take effect. However, this is for skin and body flukes. Other issues may not need as long.

What Is PRAZIPRO ; How Does It Work?

PRAZIPRO is a commercial product you can buy online or at a fish store to help control parasite infestations in your tank. This is good for both freshwater and marine aquariums as well as ponds. It’s a liquid concentrate that’s very effective at keeping diseases at bay while maintaining fish and plant health.

Gentle on Your System ; Nitrogen Cycle

PRAZIPRO is gentle on the filtration system too and won’t alter the delicate water parameter balance within the tank. Things like flukes, tapeworms and flatworms can create parasitic conditions within a tank. PRAZIPRO works to remove these to keep fish healthy and disease free.

But it works best before adding medications like an Ich treatment. Once the formula begins working, you can add the medication.

It Will Take Care of Parasites at Once

This is ideal because it will take care of all your fish and plant life at once. It will get in every nook and cranny within the environment to remove the parasitic threat. With flukes, more than one treatment will be necessary. This will not only ensure you kill the present ones but also the potential next generation lurking about in the tank.

How to Apply It to an Aquarium

You just mix fresh pretreated and conditioned tank water with the proper dosage of PRAZIPRO. Do a partial water change with a siphon and add the medicine-laced water to the tank. Do this twice per day until you see the problem clear up.

What’s the Right Dosage of PRAZIPRO?

The right dosage of PRAZIPRO will come from the tank’s size. You can figure it will be one teaspoon (about 5 milliliters) for a 20 gallon tank. What’s nice is if you end up using a little too much, it shouldn’t be any cause for concern.

You will be able to find thorough instructions on the bottle and you can contact the company directly if you have any questions. However, you can use the reference below as a guideline to help devise a plan of action:

  • 10 gallons: ½ teaspoon (about 3½  mL)
  • 20 gallons: one teaspoon (5 mL)
  • 30 gallons: 1½ teaspoons (just over 7 mL)
  • 40 gallons: 2 teaspoons (just under 10 mL)
  • 50 gallons: 2½ teaspoons (just over 12½ mL)
  • 75 gallons: 3¾ teaspoons (just under 8½ mL)
  • 100 gallons: just over ¾ ounce, or 5 teaspoons (just over 24½ mL)
  • 120 gallons: 1 ounce, or 6 teaspoons (just over 29½ mL)
  • 480 gallons: 4 ounces, or ½ cup (118⅓ mL)
  • Ponds: 16 ounces, or 2 Cups (just over 473 mL) – in the case of ponds, one teaspoon per 32 gallons of water

What Length of Time Do You Have to Wait before PRAZIPRO Works?

If you follow the correct dosage and give it twice per day for four to five days, you will begin to see improvement. However, it depends on how bad the problem is. This recommendation is for flukes, particularly on the skin and body of fish.

In the case the issue is very minimal, then it could begin working in as little as two to three days. That said, you should be able to see improvements after one or two doses.


PRAZIPRO can be a great aid to killing and removing parasites from your aquarium. It takes just a little bit of patience depending on how bad the parasitic problem is. It can take as little as two days for minor problems but as much as five for more serious infestations.

See Also:
Is Mold Bad for Fish Tanks? Read This First!
Will Magic Eraser Kill Fish? (A Detailed Explanation)
How Long Does It Take for Dry Rock to Become Live?
How Long Does Diatom Bloom Last?